This study explores the impact of the integration of nanobiotechnology with plants in the fields of agriculture, health, and environmental management. Interactions between nanoparticles and plant components offer innovative applications for improving plant health, while gene-editing technologies like CRISPR play a significant role in enhancing plant traits. The work thoroughly examines the environmental impacts, safety, and ethical dimensions of nanobiotechnology, providing suggestions for future research areas. It also evaluates the potential effects on sustainable agriculture and food security.