Burnout is a process that has undesirable consequences in a personal and professional context and is a reaction that occurs as a result of working under pressure and facing stressful situations. Nurses who provide one-to-one care to people are seen as a stressful profession and are at risk for burnout. In the literature review, it is seen that burnout is quite common in nurses who provide one-to-one service to people and have to provide treatment and care in stressful environments. Especially during the COVID 19 pandemic, nurses have been one of the groups most affected by burnout since they are on the front lines of the patient care process. The COVID 19 pandemic has brought with it many challenges that will negatively affect healthcare professionals, especially nurses, physically and mentally globally. Increasing workload and the unknown of the disease process, the discomfort of the protective equipment constantly used for protection, the fear of transmitting the disease to oneself, one's family and those around them, the lack of a definitive and clear treatment plan for the disease, the insufficient information environment and the crisis in the health system cause fear and anxiety in nurses, causing individual and caused professional burnout. As a result, looking at the literature, burnout has become an important individual and professional problem faced by healthcare professionals and especially nurses serving positive cases during the pandemic period. It is extremely important to detect burnout syndrome, which is likely to occur in nurses working with great sacrifice in this risky process, due to the unknowns and difficulties brought by the process, at an early stage, and to take the necessary precautions and take initiatives to effectively continue the fight against similar situations such as the COVID 19 pandemic.