VAC (Vacuum-Assisted Closure) Applications in the Treatment of Diabetic Foot
Chapter from the book:
Karakurt,
P.
&
Fırat,
M.
(eds.)
2025.
Current Approaches in The Field of Health.
Synopsis
Diabetic foot ulcers are among the most serious complications of diabetes mellitus, significantly increasing both morbidity and mortality. Approximately 15–25% of diabetic patients experience a foot ulcer at least once in their lifetime. When not properly managed, these ulcers may lead to severe complications such as infection, sepsis, gangrene, and major amputations. A multidisciplinary approach is essential in diabetic foot management, including metabolic control, infection treatment, restoration of vascular circulation, and effective wound care strategies. In recent years, negative pressure wound therapy (VAC/NPWT) has become widely used and has shown superior outcomes compared to standard wound care. VAC therapy promotes wound healing by removing exudate, reducing edema, controlling bacterial load, and stimulating granulation tissue through controlled negative pressure. Proper wound bed preparation, including debridement and infection control, is crucial before initiating VAC therapy. Foam selection and pressure settings should be individualized according to the patient’s condition. VAC therapy is particularly effective in large ulcers, amputation sites, and infected wounds. Numerous clinical studies have demonstrated that VAC accelerates wound closure, enhances granulation tissue formation, and reduces the need for major amputations. However, its disadvantages include relatively high cost and potential tissue damage if used incorrectly. In conclusion, VAC therapy has become an important component in the management of diabetic foot ulcers when combined with appropriate patient selection and a multidisciplinary treatment approach.
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Copyright (c) 2025 Papatya Karakurt- Meryem Fırat; Amine Nur Arıkan- Ayçin Köycekaş- Yahya Ateşpolat- Müdriye Yıldız Bıçakçı- Arif Caner Erdoğan- Bilgenur Karaçor- Mehmet Elmalı- Bürke Çırçırlı- Mert Can Emre- Cihan Adanaş- Sezai Özkan- Elem Kocaçal- Ertuğrul Sarı- İlyas Ün- Esra Kuran- Eren Canbolat- Mahir Coşkun- Azad Duman- Merve Kandazoğlu Erdem- Betül Karabudak- Simge Erdal- Meryem Fırat- Burcu Demir Gökmen- Mine Cengiz- Naime Çelik- Rauf Melekoğlu- Ayse Sebnem Erenler- Sanem Can Sarıoğlu- Esra Buğra- Deniz Uğur Cengiz- Selen Özdemir- Şeyda Yetginler Memiş- Ümit Topcuoğlu- Yasin Özden- Zehra Güveren- Gül Bülbül Maraş- Ahmet Utuş