Green chemistry aims to minimize the environmental impact of chemical production by developing environmentally friendly processes and materials. Plastic-derived fuels make it possible to utilize waste plastics by combining them with biomass or other renewable resources for energy generation. The use of such fuels in biomass power plants supports waste management efforts while reducing dependency on fossil fuels. Plastic fuels can be blended with biomass-derived fuels through green chemistry technologies such as pyrolysis or gasification. Their application in internal combustion engines or power generation facilities should be optimized in terms of combustion efficiency and emission control. However, the equipment involved in these processes- such as fuel feeding systems, reactors, filters, and high-temperature and high-pressure fittings- may be exposed to chemicals, extreme heat, and potentially toxic gases. From an occupational health and safety (OHS) perspective, the design, ergonomics, maintenance procedures, and prevention of worker exposure to risks (chemical leaks, fire, explosion) are of critical importance. Biomass power plants, which are frequently used for the disposal of forest and agricultural residues as well as sewage sludge, are facilities containing vessels operating under high temperature and pressure. In addition to exposure to asphyxiant, irritant, or flammable dusts and/or chemicals, uncontrolled combustion and explosions can result in severe consequences for both the environment and human health. Furthermore, during the conversion of combustion energy into electrical energy, workers may face risks of electric shock, as well as exposure to high-frequency vibration and/or noise, which may lead to temporary or permanent disabilities. This section addresses the safe integration of green chemistry principles in biomass power plants, focusing on how equipment used in combustion and energy production processes can be designed and optimized to minimize environmental and health risks, ensure compliance with OHS standards, and safeguard worker safety. Building on existing practices, a comprehensive evaluation of risks encountered in biomass plants and their integration into OHS management systems is presented, taking into account the perspectives of employers, employees, and environmental factors.