Surgical Treatment of Medically Intractable Temporal Lobe Epilepsy
Chapter from the book: Gölcük, Y. (ed.) 2025. Interdisciplinary Perspectives and Clinical Reflections in Health Sciences.

Gönül Güvenç
Muğla Sıtkı Koçman University

Synopsis

In patients with medically resistant temporal lobe epilepsy, surgical resection of the epileptogenic focus is an important treatment option. In adult patients, nearly half of the seizures are complex partial seizures, and 80% of these originate from the temporal lobe. The presence of unilateral epileptogenesis is golden standart for he selection of patients for surgery. Two-stage examinations are conducted to determine the lateralization and localization of the epileptic focus. Two-stage examinations are conducted to determine the lateralization and localization of the epileptic focus. If the data obtained from seizure semiology, video-EEG, MRI, PET,SPECT and neuropsychological examination results are sufficient, a decision for surgery is made. If the obtained data is insufficient or inconsistent with each other, semi-invasive and invasive examinations are performed. In cases where surgery is decided, the aim is both to remove the epileptic area and to preserve the functional areas of the brain. Anterior temporal lobectomy and amygdalohippocampectomy are the most commonly performed surgical techniques in patients with drug-resistant temporal lobe epilepsy. In this article, we aimed to review the non-invasive, semi-invasive, and invasive examinations used in the selection of patients for surgery, surgical techniques, the outcomes of temporal lobe epilepsy surgery, and the evaluation of these outcomes.

How to cite this book

Güvenç, G. (2025). Surgical Treatment of Medically Intractable Temporal Lobe Epilepsy. In: Gölcük, Y. (ed.), Interdisciplinary Perspectives and Clinical Reflections in Health Sciences. Özgür Publications. DOI: https://doi.org/10.58830/ozgur.pub779.c3249

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Published

June 25, 2025

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