This chapter addresses chemical risk management in the textile and wood dyeing industries. Chemicals such as heavy metals, volatile organic compounds, and synthetic dyes, particularly in SMEs, pose significant risks to worker health and the environment. The study proposes the "Chemical Risk to Welfare Model" as a systematic approach for identifying and managing these risks. Innovative solutions, including natural dyes, water-based paints, and bio-based chemicals, effectively reduce toxic substances. Occupational health and safety practices such as engineering controls, personal protective equipment, and training protect workers and minimize environmental impacts. Integrating chemical risk management, occupational health and safety, and sustainability practices contributes positively to worker health, environmental protection, and economic efficiency. The study provides practical recommendations to enhance chemical risk management in SMEs.